ABSTRACT
Oxidative stress as a consequence of aging can induce infertility in males. In this study, we have investigated the effects of aging on sperm parameters, intra-spermatic water soluble antioxidants, reactive oxygen species [ROS], and in vitro blastocyst formation. We chose 5 older NMRI male mice [10-12 months] and 5 younger NMRI male mice [2-3 months]. Sperm parameters, ROS, soluble antioxidants level and in vitro fertilization rate were assessed in both groups. The results were analyzed by the independent sample and chi square tests. A correlation test was performed between ROS generation and soluble antioxidant levels. Our data showed a significant decrease [P